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Wave aims for monthly dosing with RNA editing treatment for AATD now targets a monthly injection schedule for its WVE‑006 program in AATD.

on May 20, 2026

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Wave Life Sciences is advancing an investigational RNA editing therapy, WVE-006, for alpha‑1 antitrypsin deficiency (AATD) with the goal of enabling monthly subcutaneous dosing.

Sources:

WVE-006 (GalNAc-RNA Editing) Achieves MZ-Like Phenotype ...

Sanofi, Wave post updates in race to end AATD's 40-year drought

Wave Life Sciences' RNA Editing Therapy Shows Promising R...

RNA editing for the treatment of alpha-1 antitrypsin deficiency - PMC

RNA Editing Therapy Shows Positive Proof-of-Mechanism Results ...

Wave Crashes Despite Successful RNA Editing in AATD Study

RNA Single-base Editing Therapy that Treats Genetic Lung and ...

Wave Life Sciences Announces Data From 200 Mg Single ...

Study Details | NCT06405633 | A Phase 1b/2a, Open-label Single ...

Wave shares sink on new study results for RNA editing drug

New Data - March 26,2026

Reimagining RNA medicine

[PDF] RNA Editing for the Treatment of Alpha-1 Antitrypsin Deficiency ...

Wave Life Sciences Announces Positive Update from Ongoing ...

Wave Life Sciences Reports Mixed Results in RNA Editing Trial for ...

alpha 1-Antitrypsin Deficiency dosing monthly RNA Editing Wave Life Sciences

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