Roche Takes $20M 'Leap of Faith' on C4 Therapeutics' Antibody-Targeted Degraders

Roche invested $20 million in C4 Therapeutics to advance antibody-targeted protein degraders (ATPDs).

The deal includes potential milestone payments up to $150 million and royalties on future sales.

ATPDs combine targeted protein degradation with antibody delivery for enhanced precision in oncology.

Announcement made in early 2026, highlighting Roche's commitment to next-gen degradation therapies.

C4T's platform aims to degrade disease-causing proteins more effectively than traditional PROTACs.

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